The pica is a unit of length in the field of typography and uses the symbol pc.
There are 12 points in 1 pica. 1 pica represents approximately 1/6 of an inch.
Picas are expressed using numbers and a lower case p on software such as Adobe InDesign - for example 8p6 which would represent 8 picas and 6 points (or 8.5 picas).
The Pica is very useful in measuring and calculating the space needed to print letters and words on paper - for example when laying out books or magazine articles; the font lengths are quanitified by the number of characters per pica (cpp).
The em is a unit of length in the field of typography and uses the symbol em.
It is a "relative" unit and equals the currently specified point size. For example, 1 em in a 24-point typeface is equal to 24 points. This allows a typographer to specify text size relative to a base figure.
In metal type, the em was equal to the line height of the metal body. This meant the physical size of the letter could not exceed the em. In digital type, the em is a grid of arbitrary resolution so can be scaled to any point size for screen or print.